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Windsor Clinic +44 (0) 1753 668878

Cardiff Clinic +44 (0) 2920 782628


A new discovery in facial ageing addressing skin laxity, lines and wrinkles

What is Profhilo®?

Possibly the most innovative development to the Dermal Filler market in many years, this injectable “skin bio-remodelling” treatment that stimulates the production of collagen and elastin, helping to improve skin quality and hydration. It is designed as a skin laxity treatment and shown to re-model sagging and ageing tissue to deliver tighter, smoother, more youthful, glowing skin.

What is Profhilo?

Profhilo contains high concentrations of hyaluronic acid (HA). Unlike traditional HA, Profhilo is a BDDE free medical device, stabilised by a unique thermal process to deliver an injectable hyaluronic acid that boosts skin hydration while remodelling the skin. (BDDE is the standard chemical cross linking agent in HA fillers).


With a concentration of 32mg/ml of hyaluronic acid, it remains in the skin for 28 days and stimulates 4 different types of collagen and elastin, Type I and III Collagen in fibroblast, and type IV and VII collagen in keratinocytes, endogenous hyaluronic acid and elastin production.

Profhilo’s novel characteristic is it’s thermal crosslinking and low inflammatory profile; this results in a hybrid complex of high and low molecular weight hyaluronic acid which bio-remodels skin. It is not a traditional dermal filler and is often appealing to patients wishing not to have traditional dermal fillers which volumize.

To achieve a uniform effect throughout the face and neck, a standardised pattern of injection points (BAP - Bio-Aesthetic Points) is employed to divide the product into five injection sites per side of the face. This is then repeated in a second treatment 1 month later. 

Treatment is usually very comfortable - topical anaesthetic can be used if preferred. Transient erythema (redness), pain, itching, and tenderness can occur. Patients that are breast feeding, pregnant or with a known hypersensitivity to hyaluronic acid should not use this treatment.

Dr Berry is highly experienced in performing this treatment.​

Further Information

  • Profhilo contains high concentrations of hyaluronic acid, which when slowly released, stimulates collagen and elastin production and increases hydration in both the dermis and epidermis.

  • Profhilo is used most commonly to treat facial skin, but it is also very effective in treating sagging, wrinkly and ageing skin on the neck, décolletage, arms, hands and knees.

  • Profhilo is an award-winning an injectable treatment, usually administered in 2 treatments sessions, 4 weeks apart. Each session consists of a series of injections to the treated area. 

  • Profhilo’s low inflammatory profile, coupled with its clinically proven pro-healing properties means it is very safe and requires minimal downtime.

  • Profhilo sits somewhere between a skin booster and a dermal filler. It delivers hyaluronic acid via a 2ml syringe to a depth 3mm into the skin. The gel like formula flows through the skin stimulating collagen and elastin to rapidly provide smoother, glowing skin.

Further Information
Summary and FAQs
  • What are the payment options?
    We accept cash and all major credit cards, including American Express. We do not except bank transfers or cheques unfortunately.
  • Is there parking at the clinic?
    There is available parking at both our clinics. The Windsor clinic has a limited number of spaces in front of the clinic, and further street parking. The Cardiff clinic has on street parking. Once you know where we are, finding a space to park is rarely an issue.
  • Who we share your data with
    We will not release your personal information to third parties unless we have your permission or are required by law to do so (please see below). You may request details of personal information, which we hold about you under the Data Protection Act 1998. A small fee will be payable. If you would like a copy of the information held on you please write to The Wellfield Skin Clinic.
  • How long we retain your data
    Personal information data is held for 10 years. If you leave a comment on thwe site, the comment and its metadata are retained indefinitely. This is so we can recognize and approve any follow-up comments automatically instead of holding them in a moderation queue. For users that register on our website (if any), we also store the personal information they provide in their user profile. All users can see, edit, or delete their personal information at any time (except they cannot change their username). Website administrators can also see and edit that information.
  • What rights you have over your data
    If you have an account on this site, or have left comments, you can request to receive an exported file of the personal data we hold about you, including any data you have provided to us. You can also request that we erase any personal data we hold about you. This does not include any data we are obliged to keep for administrative, legal, or security purposes.
  • Where we send your data
    Visitor comments may be checked through an automated spam detection service.
  • How we protect your data
    All paper records are kept in locked filing cabinets. Electronic information including photos are stored on electronic devices protected by passwords.
  • What data breach procedures we have in place
    Although rare, situations may arise that require confidentiality to be breached. These include times when there is a risk to an individual, employee or public or when it is against the law to withhold the information. In these circumstances information may be divulged to external agencies e.g. police, social services.
  • Chaperones for Consultations and Examinations
    Please refer to our leaflet below: .

Treatment objective


To smooth, tighten and lift the skin, improving texture and laxity.

Time required for treatment


Each treatment consists of either 2 or 3 treatment sessions, given 4 weeks apart and each lasting approximately 15 minutes.

How long until treatment results are visible?

Full results are seen in 4-6 weeks following your last treatment.


Minimal downtime is required for this treatment, although for 8-24 hours you will have raised areas.

How long will the results last for?

Results will usually last for a minimum of 6 months and will continue with maintenance. 

Treatment Timescale



Associated Treatments
Associated Conditions
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