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Windsor Clinic +44 (0) 1753 668878

Cardiff Clinic +44 (0) 2920 782628


A new discovery in facial ageing addressing skin laxity, lines and wrinkles

What is Profhilo®?

Possibly the most innovative development to the Dermal Filler market in many years, this injectable “skin bio-remodelling” treatment that stimulates the production of collagen and elastin, helping to improve skin quality and hydration. It is designed as a skin laxity treatment and shown to re-model sagging and ageing tissue to deliver tighter, smoother, more youthful, glowing skin.

What is Profhilo?

Profhilo contains high concentrations of hyaluronic acid (HA). Unlike traditional HA, Profhilo is a BDDE free medical device, stabilised by a unique thermal process to deliver an injectable hyaluronic acid that boosts skin hydration while remodelling the skin. (BDDE is the standard chemical cross linking agent in HA fillers).


With a concentration of 32mg/ml of hyaluronic acid, it remains in the skin for 28 days and stimulates 4 different types of collagen and elastin, Type I and III Collagen in fibroblast, and type IV and VII collagen in keratinocytes, endogenous hyaluronic acid and elastin production.

Profhilo’s novel characteristic is it’s thermal crosslinking and low inflammatory profile; this results in a hybrid complex of high and low molecular weight hyaluronic acid which bio-remodels skin. It is not a traditional dermal filler and is often appealing to patients wishing not to have traditional dermal fillers which volumize.

To achieve a uniform effect throughout the face and neck, a standardised pattern of injection points (BAP - Bio-Aesthetic Points) is employed to divide the product into five injection sites per side of the face. This is then repeated in a second treatment 1 month later. 

Treatment is usually very comfortable - topical anaesthetic can be used if preferred. Transient erythema (redness), pain, itching, and tenderness can occur. Patients that are breast feeding, pregnant or with a known hypersensitivity to hyaluronic acid should not use this treatment.

Dr Berry is highly experienced in performing this treatment.​

Further Information

  • Profhilo contains high concentrations of hyaluronic acid, which when slowly released, stimulates collagen and elastin production and increases hydration in both the dermis and epidermis.

  • Profhilo is used most commonly to treat facial skin, but it is also very effective in treating sagging, wrinkly and ageing skin on the neck, décolletage, arms, hands and knees.

  • Profhilo is an award-winning an injectable treatment, usually administered in 2 treatments sessions, 4 weeks apart. Each session consists of a series of injections to the treated area. 

  • Profhilo’s low inflammatory profile, coupled with its clinically proven pro-healing properties means it is very safe and requires minimal downtime.

  • Profhilo sits somewhere between a skin booster and a dermal filler. It delivers hyaluronic acid via a 2ml syringe to a depth 3mm into the skin. The gel like formula flows through the skin stimulating collagen and elastin to rapidly provide smoother, glowing skin.

Further Information
Summary and FAQs

Treatment objective


To smooth, tighten and lift the skin, improving texture and laxity.

Time required for treatment


Each treatment consists of either 2 or 3 treatment sessions, given 4 weeks apart and each lasting approximately 15 minutes.

How long until treatment results are visible?

Full results are seen in 4-6 weeks following your last treatment.


Minimal downtime is required for this treatment, although for 8-24 hours you will have raised areas.

How long will the results last for?

Results will usually last for a minimum of 6 months and will continue with maintenance. 

Treatment Timescale



Associated Treatments
Associated Conditions
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